

Further information can be found under 'Digital image integrity' which are detailed on our Standards of Reporting page. The manuscript's figure legends should state that 'Full-length blots/gels are presented in Supplementary Figure X'. These uncropped images should indicate where they were cropped, be labelled as in the main text and placed in a single supplementary figure.

Corresponding uncropped full-length gels and blot must be included in the supplementary files. In such cases, the cropping of the blot must be clearly evident and must be mentioned in the figure legend. Image integrity and standards: Cropped gels and blots can be included in the main text if it improves the clarity and conciseness of the presentation.

At the minimum, at least the corresponding author and submitting author should provide an institutional email address.
